It should be used cautiously in pets with liver disease, that are pregnant or lactating, or have uncontrolled diabetes or other conditions that cause blood electrolyte imbalances.Īre there any drug interactions I should be aware of? Do not use in pets that are not urinating or in pets that may be used for breeding. Spironolactone should not be used in pets that are allergic to it or in pets with elevated potassium levels, Addison’s disease, acute kidney failure, or significant kidney disease. This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease.Īre there any risk factors for this medication? Serious side effects include facial itchiness, rash/skin sores, persistent vomiting or diarrhea, severe tiredness, fast heartbeat, difficulty walking, collapse, loss of balance, lack of appetite, or lack of urinating. Other possible side effects include breast tissue growth in males. The most common side effects include increased drinking and urinating, mild decreases in energy, mild electrolyte imbalances, or vomiting and diarrhea. Never give your pet two doses at once or give extra doses. If you miss a dose, give it when you remember, but if it is close to the time for the next dose, skip the dose you missed and give it at the next scheduled time, and return to the regular dosing schedule. What if I miss giving my pet the medication? This medication should take effect within 1 to 2 hours however, effects may not be visibly noticeable and therefore laboratory tests may need to be done to evaluate this medication’s effectiveness. Because this medication causes more frequent urination, do not give the last dose of the day close to bedtime to reduce the need to let your pet out to urinate. Allow your pet access to clean and plentiful water at all times while giving this medication. It can be given with or without food however, if your pet vomits when dosed on an empty stomach, give future doses with food. It may also be compounded into a liquid form measure liquid forms carefully. Spironolactone is given by mouth in the form of a tablet. In these instances, follow your veterinarian’s directions and cautions very carefully as their directions may be significantly different from those on the label. Many drugs are commonly prescribed for off label use in veterinary medicine. Its use in cats and dogs to treat heart failure and other cardiovascular conditions is ‘off label’ or ‘extra label’. It has also been used to treat fluid accumulation in the abdomen and may be effective for treating kidney disease or high blood pressure. Spironolactone (brand names: Aldactone®, Prilactone®, Tempora®, CaroSpir®) is a potassium sparing diuretic used as an adjunctive therapy to treat congestive heart failure.
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